Evaluation and treatment of anovulatory and unexplained infertility.
نویسندگان
چکیده
Anovulatory disorders are a primary cause of female infertility. Polycystic ovarian syndrome is the major cause of anovulation and is generally associated with obesity. Lifestyle changes to encourage weight loss are the initial therapy for overweight and obese patients, followed by clomiphene citrate for ovulation induction. For those patients who fail to ovulate on clomiphene citrate, alternatives, such as letrozole; gonadotropins; and complimentary agents to enhance clomiphene citrate, such as metformin and glucocorticoids, are reviewed. Women with unexplained infertility (no identifiable cause of infertility on a routine evaluation) may benefit from ovulation induction with clomiphene citrate, letrozole, or gonadotropins.
منابع مشابه
Comparative evaluation of pregnancy outcome in gonadotrophin-clomiphene combination vs clomiphene alone in polycystic ovarian syndrome and unexplained infertility–A prospective clinical trial
OBJECTIVES A large prospective clinical trial was conducted to compare the efficacy of single dose uFSH and clomiphene citrate combination with clomiphene citrate alone for ovulation induction to improve the pregnancy rate. MATERIALS AND METHODS The study was a randomized, prospective clinical trial. Totally, 1527 infertile women (4381 cycles) with polycystic ovarian syndrome (PCOS) (n=911/25...
متن کاملI-33: Role of Hysteroscopy in the Diagnosis and Infertility Treatment
Abnormalities of the uterine cavity can be a contributing cause of subfertility, and assessment of this factor has been suggested as a routine investigation in the evaluation of subfertile women. Hysterosalpingography has been used as the most common procedure in the investigation of infertility cause. Saline infusion sonohysterography can show uterine cavity abnormalities, which is highly sens...
متن کاملEffect of Pertubation on Pregnancy Rates before Intrauterine Insemination Treatment in Patients with Unexplained Infertility
متن کامل
P-7: Sperm DNA Assessment as A Tool for Partial Resolver of The Unexplained Infertility Problem
Background: To establish importance of sperm DNA assessment in resolving the unexplained infertility problem. Materials and Methods: This article is based on the careful observation of texts and papers from 2000-2014 about the DNA damage assessment as a significant parameter of sperm function test. Results: Acidic Aniline blue, Sperm Chromatin Dispersion test(SCD), Malondialdehyde concentration...
متن کاملKisspeptin, unexplained infertility and embryo implantation
Objective The primary objective of the study was to compare baseline KP levels in females with different causes of infertility and then correlate it with the risk of failure to conceive, preclinical abortion and pregnancy after intracytoplasmic sperm injection (ICSI). MaterialsAndMethods AA longitudinal cohort study was carried out from August 2014 till May 2015 recruiting one hundred and twent...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Obstetrics and gynecology clinics of North America
دوره 39 4 شماره
صفحات -
تاریخ انتشار 2012